Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425649Generated: October 28, 2026

3-(piperazin-1-yl)propanoic acid → HCID 11520402, compound

https://huagongshe.com/reaction/2425649

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(piperazin-1-yl)propanoic acidHCID 1837374—
Reactant(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
ProductHCID 11520402HCID 11520402—

Reaction Steps

3-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-propionic acid hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 3-piperazin-1-yl-propionic acid in an analogous manner as described in example 25. LR-MS: 651.4 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-679e1682351547bda4f8656e310dea96
Source noteuspto-grants-2011_06