HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Piperazin-1-yl)propanenitrile → HCID 11513095, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Piperazin-1-yl)propanenitrile | HCID 2052050 | — |
| Reactant | (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57732375 | — |
| Product | HCID 11513095 | HCID 11513095 | — |
Reaction Steps
3-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-propionitrile hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 3-piperazin-1-yl-propionitrile (example 16f) in an analogous manner as described in example 25. LR-MS: 632.4 [(M+H)+]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964724B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-8c10cdf37ae741199b5ffd00122a729d |
| Source note | uspto-grants-2011_06 |