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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425656Generated: October 28, 2026

HCID 16769368, compound → HCID 11707472, compound

https://huagongshe.com/reaction/2425656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 16769368HCID 16769368—
Reactant(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
ProductHCID 11707472HCID 11707472—

Reaction Steps

1-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-3,3-dimethyl-butan-2-one hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 3,3-dimethyl-1-piperazin-1-yl-butan-2-one (example 16j) in an analogous manner as described in example 25. LR-MS: 677.5 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-3a2e561022b649fab182ac9795df867c
Source noteuspto-grants-2011_06