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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425657Generated: October 28, 2026

1-(3-(Methylsulfonyl)propyl)piperazine → HCID 11672170, compound

https://huagongshe.com/reaction/2425657

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-(Methylsulfonyl)propyl)piperazineHCID 49853478—
Reactant(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
ProductHCID 11672170HCID 11672170—

Reaction Steps

[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazol-1-yl]-[4-(3-methanesulfonyl-propyl)-piperazin-1-yl]-methanone hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 1-(3-methanesulfonyl-propyl)-piperazine (example 16e) in an analogous manner as described in example 25. LR-MS: 699.3 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-51bab0b6683c41d0bd08db727c3392ef
Source noteuspto-grants-2011_06