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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425658Generated: October 27, 2026

HCID 28378705, compound → HCID 11693434, compound

https://huagongshe.com/reaction/2425658

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 28378705HCID 28378705—
Reactant(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
ProductHCID 11693434HCID 11693434—

Reaction Steps

2-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-[1,4]diazepan-1-yl}-1-morpholin-4-yl-ethanone hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 2-[1,4]diazepan-1-yl-1-morpholin-4-yl-ethanone (example 20a) in an analogous manner as described in example 25. LR-MS: 720.5 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-f7748622478f4f4fad2983570b56d282
Source noteuspto-grants-2011_06