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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425711Generated: November 3, 2026

HCID 67248125, compound → HCID 86761345, compound

https://huagongshe.com/reaction/2425711

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67248125HCID 67248125—
ReactantHCID 86761342HCID 86761342—
ProductHCID 86761345HCID 86761345—

Reaction Steps

N-(2-{4-[(4S,5R)-2-[4-tert-Butyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-ethyl)-acetamide hydrochloride was prepared from (4S,5R)-2-[4-tert-butyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 12l) and N-(2-piperazin-1-yl-ethyl)-acetamide hydrochloride (example 23) in an analogous manner as described in example 25. LR-MS: 718.5 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-cd27e765cb8b45048091a4cbd39bd193
Source noteuspto-grants-2011_06