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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425716Generated: November 3, 2026

4-Morpholinopiperidine → HCID 11657589, compound

https://huagongshe.com/reaction/2425716

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MorpholinopiperidineHCID 795724—
Reactant(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
ProductHCID 11657589HCID 11657589—

Reaction Steps

[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-morpholin-4-yl-piperidin-1-yl)-methanone was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 4-morpholinopiperidine (Aldrich) in an analogous manner as described in example 25. HR-MS (ES, m/z): observed 663.2859, calculated for C37H45Cl2N4O3 [(M+H)+] 663.2863.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-ebf95887c6fb42dc8093ea81d849674d
Source noteuspto-grants-2011_06