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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425718Generated: November 3, 2026

N,N-Dimethylpiperidin-4-amine → HCID 67246655, compound

https://huagongshe.com/reaction/2425718

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethylpiperidin-4-amineHCID 417391—
Reactant(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
ProductHCID 67246655HCID 67246655—

Reaction Steps

[2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazol-1-yl]-(4-dimethylamino-piperidin-1-yl)-methanone hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 4-dimethylaminopiperidine (Aldrich) in an analogous manner as described in example 25. HR-MS (ES, m/z): observed 621.2755 calculated for C35H42Cl2N4O2 [(M+H)+] 621.2758.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-f70bd6c9a5a84239a1777a5d05fbdee1
Source noteuspto-grants-2011_06