HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylimidazole → N-(4-iodobenzyl)-N-valeryl-L-valine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | Valeryl chloride | HCID 61186 | — |
| Reactant | HCID 67247072 | HCID 67247072 | — |
| Product | N-(4-iodobenzyl)-N-valeryl-L-valine | HCID 67245353 | 64% |
Reaction Steps
In a manner similar to Example 5 and starting from 800 mg (2.40 mmol) of N-(4-iodobenzyl)-L-Valine, 0.47 mL (3.84 mmol) of valeryl chloride and 296 mg (3.60 mmol) of 2-methylimidazole, 635 mg (64%) of N-(4-iodobenzyl)-N-valeryl-L-Valine is obtained. The solid is recrystallised from a mixture of EtOH:H2O 1:1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964749B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-7a8d1d2e6c6841aa9468855acc288da2 |
| Source note | uspto-grants-2011_06 |