Oxalic Acid → 5-Chloro-N-({1-[(4-hydroxytetrahydro-2H-pyran-4-YL)methyl]piperidin-4-YL}methyl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide ethanedioate

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A mixture of 5-chloro-N-({1-[(4-hydroxytetrahydro-2H-pyran-4-yl)methyl]piperidin-4-yl}methyl)-1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxamide (27 mg, 0.057 mmol, example 1) and oxalic acid (5.2 mg, 0.057 mmol) was dissolved in methanol and stirred for 1 h. The mixture was concentrated and crystallized from diisopropyl ether to give 6.5 mg (20%) of the title compound as a white solid.

Provenance & Evidence