Hydrochloric Acid → HCID 67147347, compound

Participants

Reaction Steps

To a solution of N-(2-(methylsulfonyl)-5-(piperazin-1-yl)phenyl)benzo[b]thiophen-3-amine (0.05 mmol) in dichloromethane (2 mL) at 0° C. was added 30 μL of 2 M HCl in diethyl ether. The solution was allowed to stir for 10 minutes after which a precipitate formed. The solvent was removed by rotary evaporation to collect the title compound in 91% yield. 1H NMR (400 MHz, CD3OD): δ 8.24 (s, 1H), 7.98 (m, 1H), 7.65 (d, 1H), 7.54 (m, 2H), 7.22 (s, 1H), 6.49 (m, 2H), 3.20 (s, 3H), 3.17 (m, 4H), 2.94 (m, 4H); MS (ESI) m/z: 388.2 (M++1).

Provenance & Evidence