HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-2-Methyl-2-butenal → (7r)-3,3'-Dimethyl-2',5'-dioxo-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-2-Methyl-2-butenal | HCID 5321950 | — |
| Reactant | (7R)-3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2-carbaldehyde | HCID 57774205 | — |
| Solvent | Water | HCID 962 | — |
| Product | (7r)-3,3'-Dimethyl-2',5'-dioxo-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2-carbaldehyde | HCID 57955388 | — |
Reaction Steps
Essentially following the procedures described for Intermediate 13, but using trans-2-methyl-2-butenal in place of crotonaldehyde, the title compound was prepared. MS: m/z=327 (M+1+H2O).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968540B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-b68833ebae2a45eba87ca03c0e97a402 |
| Source note | uspto-grants-2011_06 |