反应详情

A solution of 11-(4-fluorobenzyl)-9-methoxy-2-methyl-3,4,5,6,12,13-hexahydro-2H[1,4]diazocino[2,1-a]-2,6-naphthyridine-1,8,10(11H)-trione (27 mg, 0.07 mmol) in 30% hydrobromide in acetic acid was stirred at room temperature for 30 minutes. The reaction mixture was concentrated under vacuum. The residue was concentrated from a solution in toluene twice. The resultant solid was triturated with a mixture of diethyl ether and dichloromethane to provide the title compound.

1. concentrationThe reaction mixture was concentrated under vacuum
2. concentrationThe residue was concentrated from a solution in toluene twice
3. customThe resultant solid was triturated with a mixture of diethyl ether and dichloromethane