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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2426612Generated: November 2, 2026

Methyl iodide → tert-Butyl (R)-methyl-[1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate

https://huagongshe.com/reaction/2426612

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactanttert-butyl [(3R)-1-(4-nitrophenyl)pyrrolidin-3-yl]carbamateHCID 86594863—
Producttert-Butyl (R)-methyl-[1-(4-nitrophenyl)pyrrolidin-3-yl]carbamateHCID 67148139—

Reaction Steps

tert-Butyl (R)-[1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate was alkylated with iodomethane by method F. This resulted in the product with the molecular weight of 321.38 (C16H23N3O4); MS (ESI): 322 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968550B2
Source datasetuspto-grants-2011_06
ORD IDord-4750df9f5a1c423f86a0a4149c7cc8a2
Source noteuspto-grants-2011_06