1-methylpiperidine-3-carboxylic Acid → HCID 12146655, compound

HRID 2426614Notes

Reaction equation

HRID 2426614 reaction equation
[CH3:1][NH:2][C@@H:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]([N:17]3[CH2:22][CH2:21][CH:20]([C:23]4[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=4)[CH2:19][CH2:18]3)=[O:16])=[CH:10][CH:9]=2)[CH2:4]1.[CH3:30][N:31]1[CH2:36][CH2:35][CH2:34][CH:33]([C:37](O)=[O:38])[CH2:32]1>>[CH3:1][N:2]([C:37]([CH:33]1[CH2:34][CH2:35][CH2:36][N:31]([CH3:30])[CH2:32]1)=[O:38])[C@@H:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:9]=[CH:10][C:11]([NH:14][C:15]([N:17]3[CH2:18][CH2:19][CH:20]([C:23]4[CH:24]=[CH:25][C:26]([Cl:29])=[CH:27][CH:28]=4)[CH2:21][CH2:22]3)=[O:16])=[CH:12][CH:13]=2)[CH2:4]1

Participants

3

Reactant 2

HCID 27369371-methylpiperidine-3-carboxylic AcidHCID 58867492HCID 58867492, compound

Product 1

HCID 12146655HCID 12146655, compound

Procedure

(R)-4-(4-Chlorophenyl)piperidine-1-carboxylic acid [4-(3-methylamino-pyrrolidin-1-yl)phenyl]amide was reacted with 1-methylpiperidine-3-carboxylic acid by method E. This resulted in the product with the molecular weight of 538.14 (C30H40CIN5O2); MS (ESI): 538 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 538.14 (C30H40CIN5O2)

Sources & evidence

ORD record
ord-e14cbd3796e64574a9f7fee60af812b1
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

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