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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2426623Generated: November 2, 2026

Aniline → HCID 10004660, compound

https://huagongshe.com/reaction/2426623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactantp-FluoronitrobenzeneHCID 9590—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant4-MorpholinopiperidineHCID 795724—
Reactant4-(Cyclopentyloxy)anilineHCID 6484448—
ReactantHCID 178418361HCID 178418361—
ProductHCID 10004660HCID 10004660—

Reaction Steps

4-Piperidin-4-ylmorpholine was reacted with 4-fluoronitrobenzene, the resulting nitro compound was reduced with hydrogen and finally the aniline was reacted with CDI and 4-cyclopentyloxyaniline by method A, B and C. This resulted in the product with the molecular weight of 464.61 (C27H36N4O3); MS (ESI): 465 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968550B2
Source datasetuspto-grants-2011_06
ORD IDord-cbf1d398cce04a2a9700ceaf23ae25e0
Source noteuspto-grants-2011_06