2-Butene, 1-bromo-3-methyl- → HCID 86594874, compound

HRID 2426656Notes

Reaction equation

HRID 2426656 reaction equation
[CH:1]1([C:7]2[CH:35]=[CH:34][C:10]([C:11]([NH:13][C:14]3[CH:15]=[CH:16][C:17]([N:20]4[CH2:24][CH2:23][CH:22]([CH2:25][NH:26][C:27](=[O:33])[O:28][C:29]([CH3:32])([CH3:31])[CH3:30])[CH2:21]4)=[N:18][CH:19]=3)=[O:12])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:36][C:37]([CH3:41])=[CH:38][CH2:39]Br>>[CH:1]1([C:7]2[CH:35]=[CH:34][C:10]([C:11]([N:13]([CH2:39][CH:38]=[C:37]([CH3:41])[CH3:36])[C:14]3[CH:15]=[CH:16][C:17]([N:20]4[CH2:24][CH2:23][CH:22]([CH2:25][NH:26][C:27](=[O:33])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:21]4)=[N:18][CH:19]=3)=[O:12])=[CH:9][CH:8]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 700922-Butene, 1-bromo-3-methyl-HCID 86594875HCID 86594875, compound

Product 1

HCID 86594874HCID 86594874, compound

Procedure

tert-Butyl {1-[5-(4-cyclohexylbenzoylamino)pyridin-2-yl]pyrrolidin-3-yl}methylcarbamate was reacted with 3-methyl-2-butenyl bromide by method F-a. This resulted in the product with the molecular weight of 546.76 (C33H46N4O3); MS (ESI): 547 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 546.76 (C33H46N4O3)

Sources & evidence

ORD record
ord-af8f06ad911c4f59a99d95fd8a036fa1
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

Loading…