1-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amine → HCID 178482923, compound

HRID 2426664Notes

Reaction equation

HRID 2426664 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[CH:4][N:3]=1.[NH2:11][C:12]1[CH:17]=[CH:16][C:15]([N:18]2[CH2:22][CH2:21][CH:20]([N:23]([CH3:25])[CH3:24])[CH2:19]2)=[CH:14][CH:13]=1>>[CH3:24][N:23]([CH3:25])[CH:20]1[CH2:21][CH2:22][N:18]([C:15]2[CH:16]=[CH:17][C:12]([NH:11][C:6](=[O:8])[C:5]3[CH:9]=[CH:10][C:2]([OH:1])=[N:3][CH:4]=3)=[CH:13][CH:14]=2)[CH2:19]1

Participants

3

Reactant 2

HCID 219165911-(4-aminophenyl)-N,N-dimethylpyrrolidin-3-amineHCID 178418479HCID 178418479, compound

Product 1

HCID 178482923HCID 178482923, compound

Procedure

6-Hydroxynicotinic acid was reacted with [1-(4-aminophenyl)pyrrolidin-3-yl]dimethylamine by method E-b. This resulted in the product with the molecular weight of 326.17 (C18H22N4O2); MS (ESI): 327 (M+H+) as hydrotrifluoroacetate.

Workup

  1. customThis resulted in the product with the molecular weight of 326.17 (C18H22N4O2)

Sources & evidence

ORD record
ord-a05be2962813434fa3a848913de3eea9
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

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