Acetic Anhydride → HCID 21105597, compound

HRID 2426673Notes

Reaction equation

HRID 2426673 reaction equation
[CH2:1]([O:5][C:6]1[CH:28]=[CH:27][C:9]([C:10]([N:12]([CH3:26])[C:13]2[CH:18]=[CH:17][C:16]([N:19]3[CH2:23][CH2:22][CH:21]([NH:24][CH3:25])[CH2:20]3)=[CH:15][CH:14]=2)=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4].[C:29](OC(=O)C)(=[O:31])[CH3:30]>N1C=CC=CC=1>[C:29]([CH2:25][NH:24][CH:21]1[CH2:22][CH2:23][N:19]([C:16]2[CH:17]=[CH:18][C:13]([N:12]([CH3:26])[C:10](=[O:11])[C:9]3[CH:27]=[CH:28][C:6]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])=[CH:7][CH:8]=3)=[CH:14][CH:15]=2)[CH2:20]1)(=[O:31])[CH3:30]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 21105482HCID 21105482, compound

Product 1

HCID 21105597HCID 21105597, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

4-Butoxy-N-methyl-N-[4-(3-methylaminopyrrolidin-1-yl)phenyl]benzamide was mixed with pyridine and acetic anhydride. Volatile fractions were removed after 2 hours. This resulted in the product with the molecular weight of 423.56 (C25H33N3O3); MS (ESI): 424 (M+H+).

Workup

  1. customVolatile fractions were removed after 2 hours
  2. customThis resulted in the product with the molecular weight of 423.56 (C25H33N3O3)

Sources & evidence

ORD record
ord-db85cc50c21244f093ac372ac8b6e36e
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

Loading…