1-Bromo-2-methylpropane → HCID 21105614, compound

HRID 2426682Notes

Reaction equation

HRID 2426682 reaction equation
Br[CH2:2][CH:3]([CH3:5])[CH3:4].[CH3:6][N:7]([CH3:29])[CH:8]1[CH2:12][CH2:11][N:10]([C:13]2[CH:18]=[CH:17][C:16]([NH:19][C:20](=[O:28])[C:21]3[CH:26]=[CH:25][C:24]([OH:27])=[N:23][CH:22]=3)=[CH:15][CH:14]=2)[CH2:9]1>>[CH3:6][N:7]([CH3:29])[CH:8]1[CH2:12][CH2:11][N:10]([C:13]2[CH:14]=[CH:15][C:16]([NH:19][C:20](=[O:28])[C:21]3[CH:26]=[CH:25][C:24]([O:27][CH2:2][CH:3]([CH3:5])[CH3:4])=[N:23][CH:22]=3)=[CH:17][CH:18]=2)[CH2:9]1

Participants

3

Reactant 2

HCID 65551-Bromo-2-methylpropaneHCID 178482923HCID 178482923, compound

Product 1

HCID 21105614HCID 21105614, compound

Procedure

1-Bromo-2-methylpropane was reacted with N-[4-(3-dimethylaminopyrrolidin-1-yl)-phenyl]-6-hydroxynicotinamide by method H-a. This resulted in the product with the molecular weight of 382.24 (C22H30N4O2); MS (ESI): 383 (M+H+) as hydrotrifluoroacetate.

Workup

  1. customThis resulted in the product with the molecular weight of 382.24 (C22H30N4O2)

Sources & evidence

ORD record
ord-07f89ec5e5954d38938bea9551e6c923
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

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