HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromobenzonitrile → 4-(3-Cyanophenyl)-3, 6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromobenzonitrile | HCID 23381 | — |
| Reactant | 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide | HCID 67147946 | — |
| Product | 4-(3-Cyanophenyl)-3, 6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide | HCID 58866978 | — |
Reaction Steps
4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid [4-(3-dimethylaminopyrrolidin-1-yl)phenyl]amide was reacted with 3-bromobenzonitrile by method O-a. This resulted in the product with the molecular weight of 415.54 (C25H29N5O); MS (ESI): 416 (M+H+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968550B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-acf5c4f455d8402f8496f0e7ffb150b9 |
| Source note | uspto-grants-2011_06 |