HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromomethylcyclopropane → HCID 58867422, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromomethylcyclopropane | HCID 81503 | — |
| Reactant | HCID 67148105 | HCID 67148105 | — |
| Reactant | HCID 67148281 | HCID 67148281 | — |
| Product | HCID 58867422 | HCID 58867422 | — |
Reaction Steps
(R)-4-Benzyloxy-N-[4-(3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]benzamide underwent debenzylating hydrogenation by method B. The resulting (R)-N-[4-(3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-4-hydroxybenzamide was alkylated with cyclopropylmethyl bromide by method H. This resulted in the product with the molecular weight of 397.50 (C23H28N3O2); MS (ESI): 398 (M+H+). The following examples were likewise obtained by method H:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968550B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-c0778b8d071b4c07aa7c3de709b92e70 |
| Source note | uspto-grants-2011_06 |