2-Chloropyridine → HCID 67147548, compound

HRID 2426705Notes

Reaction equation

HRID 2426705 reaction equation
[CH3:1][N:2]([CH3:25])[C@@H:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:23])[C:16]3[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=3)=[CH:10][C:9]=2[F:24])[CH2:4]1.Cl[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=1>>[CH3:1][N:2]([CH3:25])[C@@H:3]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:23])[C:16]3[CH:21]=[CH:20][C:19]([O:22][C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=4)=[CH:18][CH:17]=3)=[CH:10][C:9]=2[F:24])[CH2:4]1

Participants

3

Reactant 2

HCID 79772-ChloropyridineHCID 67148105HCID 67148105, compound

Product 1

HCID 67147548HCID 67147548, compound

Procedure

(R)-N-[4-(3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-4-hydroxybenzamide was reacted with 2-chloropyridine by method R. This resulted in the product with the molecular weight of 434.52 (C25H27N4O2); MS (ESI): 435 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 434.52 (C25H27N4O2)

Sources & evidence

ORD record
ord-ed4dea06e2f74fafa027c53a032d286b
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

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