Methyl acetoacetate → HCID 67255236, compound

HRID 2426972Notes

Reaction equation

[C:1]([O:7][CH3:8])(=[O:6])[CH2:2][C:3]([CH3:5])=O.[F:9][C:10]1[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[C:11]=1[NH2:12]>>[F:9][C:10]1[CH:16]=[CH:15][CH:14]=[C:13]([F:17])[C:11]=1[NH:12]/[C:3](/[CH3:5])=[CH:2]\[C:1]([O:7][CH3:8])=[O:6]

Participants

Reactant 2

HCID 7757Methyl acetoacetate

HCID 796472,6-Difluoroaniline

Product 1

HCID 67255236HCID 67255236, compound

Procedure

By the same procedure as a reaction of Example 158, using methyl acetoacetate and using 2,6-difluoroaniline instead of 4-chloro-2,6-dimethylaniline, the title compound having the following physical data was obtained.

Workup

customBy the same procedure as a reaction of Example 158

Sources & evidence

ORD record: ord-10f7f86958a640babec3305f9492faf7
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07968572B2

Reaction notes

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