HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-bromo-1-(3,5-dichloro-4-pyridinyl)-1H-pyrrole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1-(3,5-dichloro-4-pyridinyl)-1H-pyrrole-2-carbaldehyde | HCID 86632553 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-bromo-1-(3,5-dichloro-4-pyridinyl)-1H-pyrrole-2-carbaldehyde | HCID 86632554 | 102.1% |
Reaction Steps
To a solution of 2.14 g of 1-(3,5-dichloro-4-pyridinyl)-1H-pyrrole-2-carbaldehyde in 10 ml of N,N-dimethylformamide was added 1.7 g of N-bromosuccinimide. The mixture was stirred at room temperature for 2 hours. Water was poured into the reaction mixture, and a deposited precipitate was collected by filtration to obtain 2.9 g of 4-bromo-1-(3,5-dichloro-4-pyridinyl)-1H-pyrrole-2-carbaldehyde of the formula:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968573B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-b4eb0d4b76a94113a65099b74b59925f |
| Source note | uspto-grants-2011_06 |