HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 86632556, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1-(2-Chloro-pyridin-3-yl)-1H-pyrrole-2-carbaldehyde | HCID 2772324 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86632556 | HCID 86632556 | 50.5% |
Reaction Steps
To a solution of 6.05 g of 1-(2-chloro-3-pyridinyl)-1H-pyrrole-2-carbaldehyde in 20 ml of N,N-dimethylformamide was added 5.72 g of N-bromosuccinimide. The resulting mixture was stirred at room temperature for 1 hour. Water was poured into the reaction mixture, and a deposited precipitate was collected by filtration to obtain 4.22 g of 4-bromo-1-(2-chloro-3-pyridinyl)-1H-pyrrole-2-carbaldehyde of the formula:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968573B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-690460fb98384540bbf7cdad9cb048ca |
| Source note | uspto-grants-2011_06 |