HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2427148Generated: November 1, 2026
Ethanol → 3-[2,5-Dioxo-4-[(2-propenyloxy)methyl]imidazolidin-4-yl]benzonitrile
https://huagongshe.com/reaction/2427148
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | (2-(2-Propenyloxy)acetyl]benzonitrile | HCID 86641460 | — |
| Product | 3-[2,5-Dioxo-4-[(2-propenyloxy)methyl]imidazolidin-4-yl]benzonitrile | HCID 67131009 | — |
Reaction Steps
To a solution of 450 mg of 3-[(2-(2-propenyloxy)acetyl]benzonitrile (in EtOH (5 mL) and water (5 mL) 291 mg of potassium cyanide and ammonium carbonate are added. The mixture is refluxed one night at 55° C. The mixture is extracted with ethyl acetate, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07968581B2 |
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| Source dataset | uspto-grants-2011_06 |
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| ORD ID | ord-6a5bfc1d08ce4aa281846337c9f5e2d7 |
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| Source note | uspto-grants-2011_06 |
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