HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-(3,5-dichloro-4-(naphthalen-2-ylthio)phenyl)-4-iodobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Iodobenzenesulfonyl chloride | HCID 7399 | — |
| Reactant | 3,5-Dichloro-4-(napthalen-2-ylsulfanyl)-phenylamine | HCID 22148834 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(3,5-dichloro-4-(naphthalen-2-ylthio)phenyl)-4-iodobenzenesulfonamide | HCID 23515237 | 93% |
Reaction Steps
The title compound was prepared using the method of example 94, starting with 3,5-dichloro-4-(naphthalen-2-ylsulfanyl)-phenylamine (90) (150 mg, 0.47 mmol), pyridine (Aldrich, 0.19 mL, 2.34 mmol) and 4-iodobenzenesulfonyl chloride (Acros, 155 mg, 0.52 mmol) in THF. 254 mg (93%) of 101 was obtained as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968567B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-a7e0660833fa4ff7afc9464b9bae928d |
| Source note | uspto-grants-2011_06 |