HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → Methyl 2-(bromomethyl)-6-iodobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-Bromosuccinamide | HCID 9834204 | — |
| Reactant | Methyl 2-iodo-6-methylbenzoate | HCID 23655277 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl 2-(bromomethyl)-6-iodobenzoate | HCID 11268261 | — |
Reaction Steps
A mixture of 2-iodo-6-methyl-benzoic acid methyl ester (3.59 g, 13 mmol), N-bromosuccinamide (2.3 g, 13 mmol), and benzoyl peroxide (0.056 g, 0.21 mmol) in carbon tetrachloride (20 mL) was heated at reflux until the starting materials were mostly consumed. Workup afforded 2-bromomethyl-6-iodo-benzoic acid methyl ester. The material was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968570B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-eddb53b96fde42d4ad7b2021ae1cf61c |
| Source note | uspto-grants-2011_06 |