Dimethylacetamide → HCID 11947986, compound

Participants

Reaction Steps

A suspension of 4-bromomethyl-2′-formylbiphenyl (I) (1.2 g, 4.32 mmol), 2-(1-propyl)-4-methyl-6-(1′-methylbenzimidazol-2-yl)benzimidazole (1.1 g, 3.6 mmol) and potassium tert-butylate (0.41 g, 3.6 mmol) in 25 ml of N,N-dimethylacetamide is stirred at room temperature under argon atmosphere for 5 hours. Reaction mixture is poured in 160 ml of water and stirred for 30 minutes. Obtained precipitated solid is filtered off, suspended in 70 ml of water again, and stirred for 1 hour. Crude product is filtered off and dried in vacuum at 40° C. overnight. Yield: 1.37 g.

Provenance & Evidence