2-Bromo-5-fluoro-[1-(methoxymethoxy)methyl]benzene → HCID 11817228, compound

HRID 2427941Notes

Reaction equation

HRID 2427941 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([B:9]2[O:13][CH2:12][CH2:11]O2)=[CH:5][CH:4]=1)#[N:2].Br[C:15]1C=[CH:19][C:18]([F:21])=[CH:17][C:16]=1COCOC>>[F:21][C:18]1[CH:17]=[CH:16][C:15]2[B:9]([C:6]3[CH:5]=[CH:4][C:3]([C:1]#[N:2])=[CH:8][CH:7]=3)[O:13][CH2:12][C:11]=2[CH:19]=1

Participants

3

Reactant 2

HCID 118455732-Bromo-5-fluoro-[1-(methoxymethoxy)methyl]benzeneHCID 18541718HCID 18541718, compound

Product 1

HCID 11817228HCID 11817228, compound

Procedure

This was prepared as per the procedure in Example 11, from 2-(4-cyanophenyl)-[1,3,2]-dioxaborolane and 1-bromo-4-fluoro-2-((methoxymethoxy)methyl)benzene to afford white crystalline product.

Workup

  1. customto afford white crystalline product

Sources & evidence

ORD record
ord-ff99a59b1c5b49e2a378fddf35859d11
Source dataset
uspto-grants-2011_06
Patent number
US07968752B2

Reaction notes

Loading…