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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2428Generated: October 26, 2026

4-Nitrobenzoic Acid → 4-nitro-N-[2-(trifluoromethyl)phenyl]benzamide

https://huagongshe.com/reaction/2428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrobenzoic AcidHCID 6108—
Reactant2-(Trifluoromethyl)anilineHCID 6922—
Product4-nitro-N-[2-(trifluoromethyl)phenyl]benzamideHCID 77986915.3%

Reaction Steps

Using 2-trifluoromethylaniline (1.77 g, 11.0 mmol) and 4-nitrobenzoic acid (1.67 g, 10.0 mmol), the procedure of Reference Example 16 was repeated to obtain 474 mg (15.3%) the title compound in the form of colorless powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05728835
Source datasetuspto-grants-1998_03
ORD IDord-33162552f5a14903a0ce124e5d44dc3e
Source noteuspto-grants-1998_03