Hydrochloric Acid → HCID 131728986, compound

Participants

Reaction Steps

A sol. of compound D1 (2.00 g, 3.72 mmol) in THF (30 mL) and aq. 1M NaOH (30 mL) was stirred at 70° C. overnight. Aq. 1M HCl was added until a pH=4 was reached. The mixture was extracted with EtOAc (3×). The combined org. extracts were dried over MgSO4, filtered, and the solvents were removed under reduced pressure. Drying under high vacuum yielded the crude title compound (2.04 g, quantitative yield) that was used further without purification. LC-MS: tR=1.08 min; ES+: 549.31.

Provenance & Evidence