Cyclopropyl-[5-(2-methoxy-ethyl)-2-methyl-benzyl]-amine → (1R,5S)-7-{4-[2-(2,6-Dichloro-4-methyl-phenoxy)-ethoxy]-phenyl}-3,9-diaza-bicyclo[3.3.1]non-6-ene-6-carboxylic Acid cyclopropyl-[5-(2-methoxy-ethyl)-2-methyl-benzyl]-amide

Participants

Role	Name	HCID	Charge
Reactant	Cyclopropyl-[5-(2-methoxy-ethyl)-2-methyl-benzyl]-amine	HCID 57956091	—
Reactant	(1R,5S)-7-{4-[2-(2,6-dichloro-4-methyl-phenoxy)-ethoxy]-phenyl}-3,9-diaza-bicyclo[3.3.1]non-6-ene-3,6,9-tricarboxylic acid 3,9-di-tert-butyl ester	HCID 67149015	—
Product	(1R,5S)-7-{4-[2-(2,6-Dichloro-4-methyl-phenoxy)-ethoxy]-phenyl}-3,9-diaza-bicyclo[3.3.1]non-6-ene-6-carboxylic Acid cyclopropyl-[5-(2-methoxy-ethyl)-2-methyl-benzyl]-amide	HCID 67148691	—

Reaction Steps

This compound was synthesized from (1R,5S)-7-{4-[2-(2,6-dichloro-4-methyl-phenoxy)-ethoxy]-phenyl}-3,9-diaza-bicyclo[3.3.1]non-6-ene-3,6,9-tricarboxylic acid 3,9-di-tert-butyl ester and cyclopropyl-[5-(2-methoxy-ethyl)-2-methyl-benzyl]-amine as for compound L1, and then Example 1. MS (ESI, Q+) m/z 664.1.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07968720B2
Source dataset	uspto-grants-2011_06
ORD ID	ord-951218b242c246e3ac51a648e4e0c7d9
Source note	uspto-grants-2011_06