HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trolox → HCID 67263062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Product | HCID 67263062 | HCID 67263062 | 73% |
Reaction Steps
Following the amide coupling procedure described in protocol A, 502 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.01 mmol), 356 mg CDI (2.20 mmol) and 158 mg cyclopropanemethylamine (2.22 mmol produced 445 mg of N-(cyclopropylmethyl)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide as a clear colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968746B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-320f5b68fd9e4a8faa43824b6f01a95b |
| Source note | uspto-grants-2011_06 |