HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → ethyl 3-formyl-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | Ethyl indole-2-carboxylate | HCID 73125 | — |
| Product | ethyl 3-formyl-1H-indole-2-carboxylate | HCID 5107764 | — |
Reaction Steps
Ethyl indole-2-carboxylate (10 g, 52.8 mmol) was formylated using POCl3 (1.3 equiv.) and DMF (1.3 equiv.) as above to give 3-formyl-1H-indole-2-carboxylic acid ethyl ester as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06855730B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-1c23ee20681a4d60ab465765200aa4b8 |
| Source note | uspto-grants-2005_02 |