Oxindole → 3-(3,5-Diisopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one

HRID 24343Notes

Reaction equation

[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[NH:17]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH2:19][C:18]1=[O:26]>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=[C:19]1[C:20]2[C:25](=[CH:24][CH:23]=[CH:22][CH:21]=2)[NH:17][C:18]1=[O:26])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 321710Oxindole

HCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 543582963-(3,5-Diisopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was then condensed with 2-oxindole to give 0.25 g of 3-(3,5-Diisopropyl-4-methoxybenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record: ord-baac72e6acb944ae8b7d03a7653ebd4a
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06855730B2

Reaction notes

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