N-(2-Oxoindolin-6-yl)acetamide → N-[3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indol-6-yl]-acetamide

HRID 24347Notes

Reaction equation

HRID 24347 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[C:17]([NH:20][C:21]1[CH:29]=[C:28]2[C:24]([CH2:25][C:26](=[O:30])[NH:27]2)=[CH:23][CH:22]=1)(=[O:19])[CH3:18]>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=[C:25]1[C:24]2[C:28](=[CH:29][C:21]([NH:20][C:17](=[O:19])[CH3:18])=[CH:22][CH:23]=2)[NH:27][C:26]1=[O:30])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 2749839N-(2-Oxoindolin-6-yl)acetamideHCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 53933497N-[3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indol-6-yl]-acetamide

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 6-acetamido-2-oxindole to give 0.3 g of N-[3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indol-6-yl]-acetamide as a yellow-orange solid.

Sources & evidence

ORD record
ord-e442e7febd2840378e93515b5ae9bb06
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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