Trifluoroacetic acid → HCID 18526474, compound

Participants

Reaction Steps

To a solution of tert-butyl 4-((4-benzylmorpholin-2-yl)methyl)piperazine-1-carboxylate (165 mg) in CH2Cl2 (5 ml) is added trifluoroacetic acid (1.0 ml), and the mixture is stirred over night. The solvent is removed under reduced pressure. The residue is dissolved in CH2Cl2 and washed with an aqueous solution of potassium carbonate (20%), dried (Na2SO4) and filtered, and the solvent is removed under reduced pressure to give 4-benzyl-2-(piperazin-1-ylmethyl)morpholine (119 mg). m/z(+) 276 (M+H+).

Provenance & Evidence