HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → N-[2-(7-methoxy-1-naphthyl)ethyl]phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 7-Methoxy-1-naphthylethyl benzene sulfonate | HCID 13570067 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-[2-(7-methoxy-1-naphthyl)ethyl]phthalimide | HCID 44633448 | 80% |
Reaction Steps
The compound IV (14 g, 0.041 mol) produced as described above and potassium phthalimide (8.3 g, 0.045 mol) were added into a flask containing dimethylformamide (180 ml) as a solvent, heated and refluxed for 2 hours. After cooling the content to room temperature, 200 ml of water was added. The mixture was stirred and filtered. The filter cake formed was washed with water and dried, to produce 10.8 g of N-[2-(7-methoxy-1-naphthyl)ethyl]phthalimide (II). The yield was 80%. The melting point was 159-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653281B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-e60ec5d901e54a1b8e1a3dc01b401fa6 |
| Source note | uspto-grants-2014_02 |