反应详情

The compound IV (14 g, 0.041 mol) produced as described above and potassium phthalimide (10.8 g, 0.0574 mol) were added into a reaction vessel, and acetonitrile (150 ml) was added. The mixture was heated and refluxed for 4 hours. After cooling it to room temperature, 200 ml of water was added, and the mixture was stirred and filtered. The filter cake formed was washed with water and dried, to produce 12 g of N-[2-(7-methoxy-1-naphthyl)ethyl]phthalimide (II). The yield was 90%. The melting point was 160-160.9° C.

1. additionwere added into a reaction vessel
2. temperatureThe mixture was heated
3. temperaturerefluxed for 4 hours
4. filtrationfiltered
5. customThe filter cake formed
6. washwas washed with water
7. customdried