5-Methoxyoxindole → 3-(3,5-Diisopropyl-4-methoxybenzylidene)-5-methoxy-1,3-dihydroindol-2-one

HRID 24367Notes

Reaction equation

[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[CH3:17][O:18][C:19]1[CH:20]=[C:21]2[C:25](=[CH:26][CH:27]=1)[NH:24][C:23](=[O:28])[CH2:22]2>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=[C:22]1[C:21]2[C:25](=[CH:26][CH:27]=[C:19]([O:18][CH3:17])[CH:20]=2)[NH:24][C:23]1=[O:28])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 15142865-Methoxyoxindole

HCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 545672543-(3,5-Diisopropyl-4-methoxybenzylidene)-5-methoxy-1,3-dihydroindol-2-one

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 5-methoxy-2-oxindole to give 0.3 g of 3-(3,5-Diisopropyl-4-methoxybenzylidene)-5-methoxy-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record: ord-39a43958faee4d7fa431654b9eac6685
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06855730B2

Reaction notes

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