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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24371Generated: October 25, 2026

5-Nitro-2-oxindole → 5-Amino-2-oxindole

https://huagongshe.com/reaction/24371

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Nitro-2-oxindoleHCID 230366—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product5-Amino-2-oxindoleHCID 277321360%

Reaction Steps

5-Nitro-2-oxindole (6.3 g) was hydrogenated in methanol over 10% palladium on carbon to give 3.0 g (60% yield) of 5-amino-2-oxindole as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-0d35ead0f179470ea7c92ba164534246
Source noteuspto-grants-2005_02