5-Chlorooxindole → 5-Chloro-3-(4-methoxy-3,5-dimethylbenzylidene)-1,3-dihydroindol-2-one

HRID 24373Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([CH3:12])[C:9]=1[O:10][CH3:11])[CH:5]=O.[Cl:13][C:14]1[CH:15]=[C:16]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[CH2:17]2>>[Cl:13][C:14]1[CH:15]=[C:16]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[C:17]2=[CH:5][C:4]1[CH:3]=[C:2]([CH3:1])[C:9]([O:10][CH3:11])=[C:8]([CH3:12])[CH:7]=1

Participants

Reactant 2

HCID 1528015-Chlorooxindole

HCID 27585734-Methoxy-3,5-dimethylbenzaldehyde

Product 1

HCID 542931995-Chloro-3-(4-methoxy-3,5-dimethylbenzylidene)-1,3-dihydroindol-2-one

Procedure

3,5-Dimethyl-4-methoxybenzaldehyde was condensed with 5-chloro-2-oxindole to give 0.3 g of 5-chloro-3-(4-methoxy-3,5-dimethylbenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record: ord-48b66da3f5fd45078c7ff4667d874ebf
Source dataset: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06855730B2

Reaction notes

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