6-fluoro-2,3-dihydro-1H-indol-2-one → 3-(3,5-Diisopropyl-4-methoxybenzylidene)-6-fluoro-1,3-dihydroindol-2-one

HRID 24375Notes

Reaction equation

HRID 24375 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=O)([CH3:3])[CH3:2].[F:17][C:18]1[CH:26]=[C:25]2[C:21]([CH2:22][C:23](=[O:27])[NH:24]2)=[CH:20][CH:19]=1>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([CH:14]([CH3:16])[CH3:15])[C:11]=1[O:12][CH3:13])[CH:7]=[C:22]1[C:21]2[C:25](=[CH:26][C:18]([F:17])=[CH:19][CH:20]=2)[NH:24][C:23]1=[O:27])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 37310136-fluoro-2,3-dihydro-1H-indol-2-oneHCID 105850253,5-Diisopropyl-4-methoxybenzaldehyde

Product 1

HCID 537335703-(3,5-Diisopropyl-4-methoxybenzylidene)-6-fluoro-1,3-dihydroindol-2-one

Procedure

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 6-fluoro-2-oxindole to give 0.3 g of 3-(3,5-diisopropyl-4-methoxybenzylidene)-6-fluoro-1,3-dihydroindol-2-one as a yellow-orange solid.

Sources & evidence

ORD record
ord-9118d1b67bdd48c89d22597d7871e4ce
Source dataset
uspto-grants-2005_02
Patent number
US06855730B2

Reaction notes

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