HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehyde → 3-(2,2-Dimethylchroman-6-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-6-carbaldehyde | HCID 1797751 | — |
| Reactant | 5-fluoro-1,3-dihydro-2H-indol-2-one | HCID 3731012 | — |
| Product | 3-(2,2-Dimethylchroman-6-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one | HCID 54405461 | — |
Reaction Steps
2,2-Dimethyl-6-formylchromane (commercially available) was condensed with 5-fluoro-2-oxindole to give 0.3 g of 3-(2,2-Dimethylchroman-6-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one as a yellow-orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06855730B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-7a06d2849b7a4e5bb350a97a0b22211f |
| Source note | uspto-grants-2005_02 |