HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Doramapimod hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Doramapimod | HCID 156422 | — |
| Solvent | Water | HCID 962 | — |
| Product | Doramapimod hydrochloride | HCID 68107492 | — |
Reaction Steps
To 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea (6.38 g, 12.1 mmol), 0.1N hydrochloric acid (121 mL) and water (150 mL) was added and dissolved therein. The solvent was removed by lyophilization method to obtain 6.91 g (quantitative) of the captioned compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653304B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-71544e06ce47441885187c4bf413919e |
| Source note | uspto-grants-2014_02 |