HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-2-iodobenzoic acid → 3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-2-iodobenzoic acid | HCID 13158583 | — |
| Reactant | 3-Fluoro-2-iodobenzoic acid | HCID 22320308 | — |
| Reactant | 5-fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086948 | — |
| Product | 3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086549 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Intermediate 1, substituting for 3-fluoro-2-iodo-benzoic acid for 5-fluoro-2-iodo-benzoic acid in Step A. 1H NMR (400 MHz, CD3OD): 7.93 (s, 2H), 7.81 (d, J=8.3 Hz, 1H), 7.63-7.58 (m, 1H), 7.29 (td, J=8.9, 0.9 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653263B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-b4f4c0497aa142bda1a41c8c74733dd7 |
| Source note | uspto-grants-2014_02 |