HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodo-5-methylbenzoic acid → 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodo-5-methylbenzoic acid | HCID 142941 | — |
| Reactant | 5-Fluoro-2-iodobenzoic acid | HCID 13158583 | — |
| Reactant | 5-fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086948 | — |
| Product | 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 53260165 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Intermediate 1, substituting for 2-iodo-5-methyl benzoic acid for 5-fluoro-2-iodo-benzoic acid in Step A. 1H NMR (400 MHz, CD3OD): 7.87 (s 2H), 7.66 (d, J=1.3 Hz, 1H), 7.59 (d, J=8.2 Hz, 1H), 7.53-7.46 (m, 1H), 2.45 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653263B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-cbfbc63ea2ae4cec929f57e9d7820e4b |
| Source note | uspto-grants-2014_02 |