HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-2-iodobenzoic acid → 5-Methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-2-iodobenzoic acid | HCID 13158583 | — |
| Reactant | 2-Iodo-5-methoxybenzoic acid | HCID 14489865 | — |
| Reactant | 5-fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086948 | — |
| Product | 5-Methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086565 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Intermediate 1, substituting for 2-iodo-5-methoxy benzoic acid for 5-fluoro-2-iodo-benzoic acid in Step A. 1H NMR (400 MHz, CD3OD): 7.81 (s, J=6.4, 2H), 7.55 (d, J=8.8, 1H), 7.33 (d, J=2.9, 1H), 7.18 (dd, J=8.8, 2.9, 1H), 3.85 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653263B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-d430a844a91243a297a1682cffdca54e |
| Source note | uspto-grants-2014_02 |